Now, more than ever, we are interested in healthy-looking skin.2,3 From its surface texture and tone (colour) to elasticity and glow, for our skin to look its best, hydration is essential.1,4,5
Healthy-looking skin starts with hydration1
When hyaluronic acid levels decrease due to environmental factors or with age, this can lead to visible changes such as skin roughness, a loss of firmness, and the appearance of fine lines and wrinkles.6,7
The good news is that by delivering hyaluronic acid where it can make a real difference,8 you can improve hydration and start your journey to healthy-looking* skin.6
What is SKINVIVE™?
DEEP,† LONG-LASTING‡ SKIN HYDRATION§ FROM WITHIN7
SKINVIVE™ is a hyaluronic acid skin hydration injection that can be injected into the face, décolletage and hands9 to deliver deep† long-lasting‡ hydration§ and visibly reduce the appearance of fine lines.7,§ It hydrates‖ and refreshes¶ from within6,7,10,** for radiant,†† smooth‡‡ and healthy-looking* skin.6
A hyaluronic acid injection unlike any other11
Designed with patented technology6 from the world’s #1 brand of hyaluronic acid facial fillers,12,§§ SKINVIVE™ contains a thinner form of hyaluronic acid that easily spreads within the skin.13,14 This makes it different to other hyaluronic acid facial filler injections used to increase volume or re-contour the face.13,14
As the only hyaluronic acid injection clinically proven to boost skin hydration§ for up to 9 months,7,11,‖‖ hydrated,§ healthy-looking skin is just one treatment away with SKINVIVE™.7
How is SKINVIVE™ different to topical moisturisers?
Unlike topical moisturisers – like hyaluronic acid creams and serums – that only target the surface,15 SKINVIVE™ targets the deeper† layers of your skin to achieve natural, long-lasting‡ results.7,9
Topical moisturisers
Topical moisturisers only hydrate the surface layers of the skin and have to be applied frequently.15
SKINVIVE™ is injected into the deeper† layers of the skin, delivering hyaluronic acid where it can make a real difference.7,8
SKINVIVE™ boosts levels of
aquaporin-3,10,** a naturally-occurring
molecule that helps maintain water balance
in the skin. Increases in aquaporin signal an
increase in hydration.10,16
Boost your daily skincare routine with SKINVIVE™
By delivering deep,† long-lasting‡ hydration,7,§ SKINVIVE™ supports your existing skincare routine, including your daily cleansing, exfoliating, toning, moisturising and sun protection.17
DAILY SKINCARE ROUTINE
Cleansing
Moisturising
Exfoliating
Sun protection
Toning
HYALURONIC ACID INJECTION
Deep† hydration7,§
SMOOTH,‡‡ GLOWING†† AND HEALTHY-LOOKING* SKIN6
Find your nearest clinic
For a deep,† long-lasting‡
injectable skin hydration treatment that
helps you meet your unique beauty
goals,7,9 speak to a practitioner about
SKINVIVE™.
SKINVIVE™ by JUVÉDERM® is an injectable implant used for the treatment, by filling, of superficial cutaneous depressions such as fine lines and for additional improvement of skin quality attributes such as hydration and elasticity.9
Footnotes
- *Lasting up to 9 months as reported by 76.2% of patients. As reported by 127 of 131 patients (1 subject did not respond) in a composite satisfaction score, which includes how healthy their skin looked.6
- †Skin hydration was measured using the MoistureMeterD instrument with the XS 5 and S 15 probes (depth of effective measurement: 0.5 and 1.5 mm, respectively).7
- ‡Long lasting is up to 9 months following a single treatment.7
- §Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and top-up treatment administered at Day 30 (n=31).7
- ‖Lasting up to 9 months as reported by 70.6% of patients. As reported by 127 of 131 patients (1 subject did not respond) in a composite satisfaction score, which includes how hydrated their facial skin looked.6
- ¶Lasting up to 9 months as reported by 51.2% of patients. As reported by 127 of 131 patients (2 subjects did not respond) in a composite satisfaction score, which includes how refreshed their facial skin looked.6
- **Data derived from a prospective, non-randomised, interventional, open-label study where 11 healthy patients (men [n=2] and women [n=9]) received intradermal VYC-12L treatment on the volar forearm. Clinical probes assessed skin quality at baseline and Months 1 and 3 post-treatment. Punch biopsies were collected at Months 1 and 3 post-treatment to evaluate histologic and genomic changes.10
- ††Lasting up to 9 months as reported by 63% of patients. As reported by 127 of 131 patients in a composite satisfaction score, which includes how radiant their facial skin looked.6
- ‡‡Lasting up to 9 months as reported by 55.1% of patients. As reported by 127 of 131 patients in a composite satisfaction score, which includes how smooth their facial skin looked.6
- §§Based on HCP tracking market research involving over 1,700 HCPs from 16 international markets.12
- ‖‖Based on a search of published clinical studies of injectable HA treatments in March 2023. A duration of 9 months was established with SKINVIVE™.11
References
- Humphrey S et al. Dermatol Surg. 2021;47(7):974–981.
- Allergan Aesthetics. Data on file. Skin Health Statistics. August 2022.
- Allergan Aesthetics. Data on file. ALL-AGNA-220122. The Future of Aesthetics Global Trends Report. July 2022.
- Fisher GJ et al. Arch Dermatol. 2008;144:666–672.
- Walker M. Int J Pharm. 2022;622:121850.
- Ogilvie P et al. J Cosmet Dermatol. 2020;19(5):1065–1070.
- Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798.
- Belmontesi M et al. J Drugs Dermatol. 2018; 17(1): 83–88.
- Juvéderm® VOLITE DFU. 73655JR10. Revision 2019-09-09.
- Safa M et al. Clin Cosmet Investig Dermatol. 2022;15:411–426.
- Allergan Aesthetics. Unpublished data. SKINVIVE™ by JUVÉDERM® – 9-month duration of skin hydration in clinical trials. March 2023.
- Allergan Aesthetics. Unpublished data. JUVÉDERM®, the world’s leading brand of hyaluronic acid facial fillers. REF-108642. March 2023.
- Akinbiyi T et al. Plast Reconstr Surg Glob Open. 2020;8(10):e2763.
- Lipko-Godlewska S et al. Clin Cosmet Investig Dermatol. 2021;14:169–178.
- Purnamawati S et al. Clin Med Res. 2017;15(3-4);75–87.
- Draelos Z. J Clin Aesthet Dermatol. 2012;5(7):53–56.
- Khmaladze I et al. Clin Cosmet Investig Dermatol. 2020;13:1021–1040.
[Local markets to update reference 9 to locally available SKINVIVE™ DFU]
Models treated with SKINVIVE™. Individual results may vary.
Website produced and funded by Allergan Aesthetics, an AbbVie company.
Directions for consumers
This content is intended for [insert country name] adult (>18yrs) audience only. You should always consult a healthcare professional to help you decide if SKINVIVE™ by JUVÉDERM® is right for you and provide you with a full list of side effects.
Directions for healthcare professionals
Patients may experience potential side effects with SKINVIVE™ by JUVÉDERM® facial filter, which include inflammatory reactions (redness, oedema, erythema, etc.), haematomas, induration or nodules, staining or discolourations at injection site, etc. Please refer to SKINVIVE™ by JUVÉDERM® Directions for Use (DFU) for a full list of adverse events.4
Adverse events should be reported. Reporting forms and information can be found at [insert local reporting information details]. Adverse events should also be reported to Allergan Aesthetics [insert local contact details for AE reporting].