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Close-up of SKINVIVE™ patient Nadia’s face, with her skin looking smooth and radiant.

SKINVIVETM
Frequently Asked
Questions

Models treated with SKINVIVETM.
Individual results may vary.

In this section, you can find answers to some common questions about SKINVIVE™. If you have any other questions or would like to know if SKINVIVE™ could be right for you, our clinic locator tool can help find a practitioner in your area.

SKINVIVE™ is a smooth hyaluronic acid gel1 specifically designed to hydrate* and refresh† your skin.2

Unlike topical moisturisers, SKINVIVE™ delivers hyaluronic acid into the deeper‡ layers of your skin, so you can achieve long-lasting§ hydration‖ for up to 9 months.3,4

SKINVIVE™ can be used to treat the face, neck, and décolletage area.1

SKINVIVE™ hyaluronic acid injections are suitable for all skin types.4,5,¶ So, if you're looking to improve your skin's clarity,** smoothness,†† hydration,* radiance‡‡ or tone (colour),§§ SKINVIVE™ could be right for you.2

A single SKINVIVE™ treatment can provide deep,‡ long-lasting§ hydration‖ for up to 9 months.4 It can also visibly reduce fine lines, with results that last up to 4 months.4

Creams and serums containing hyaluronic acid are applied topically.3 This means they often have to be applied frequently, because they only hydrate the surface layers of the skin.3

In contrast, hyaluronic acid injections like SKINVIVE™ target the deeper‡ layers of your skin,4,7 delivering hyaluronic acid where it can make a real difference.4,7 This means they can offer long-lasting,§ deep‡ hydration.4,‖

Designed for skin hydration,1 SKINVIVE™ contains a thinner form of hyaluronic acid that easily spreads to deeply hydrate skin from within.8,9 This is different to facial fillers that have a thicker form of hyaluronic acid, which is more suitable to increase volume or re-contour the face.8,9

SKINVIVE™ can complement your existing skincare routine, adding deep‡ hydration‖ alongside your daily cleansing, exfoliating, moisturising and sun protection4,10 – so you can enjoy hydrated,* glowing‡‡ skin day in, day out.2

After treatment, you can expect to see results within the first month.4 SKINVIVE™ then keeps on working for up to 9 months so you can enjoy a long-lasting4,§ glow2,‡‡ day in, day out.

If you’re looking to improve dull or rough skin, SKINVIVE™ could help.2 By unleashing deep,‡ long-lasting§ hydration,4,‖ SKINVIVE™ could help you achieve smooth,†† glowing,‡‡ and healthy-looking‖‖ skin.2

When skin is dehydrated, it often appears rough in texture.11 By boosting skin hydration with SKINVIVE™, you could enjoy touchably smooth skin for up to 6 months with just one treatment.4,‖

If you're looking to tackle fine lines on your face, décolletage or hands, SKINVIVE™ could help.1 Treatment has been shown to visibly reduce fine lines, with results that last up to 4 months.4

If you’re looking to achieve a more even skin tone, SKINVIVE™ could help.2 By delivering hyaluronic acid into the deeper‡ layers of the skin,4 SKINVIVE™ has been shown to not only improve skin tone (colour),§§ but also smoothness,†† clarity,** radiance‡‡ and hydration.2,*

When skin is dehydrated, it often appears visibly dry and dull.11 SKINVIVE™ delivers hyaluronic acid into the deeper‡ layers of the skin where it could make a real difference.4,7

It also boosts levels of aquaporin-312,¶¶ – a natural occurring molecule that helps maintain water balance in the skin. Increases in aquaporin-3 signal an increase in hydration.12,13

Through this deep‡ hydration,‖ SKINVIVE can help you to achieve a healthy-looking‖‖ glow‡‡ for up to 9 months.2

SKINVIVE™ can fit into your wider aesthetic treatment plan, whether that includes other fillers, wrinkle relaxers, fat-dissolving injections, or body contouring.14

SKINVIVE™ should not be used simultaneously with laser treatment, deep chemical peels or dermabrasion. For surface peels, it is recommended not to inject the product if the inflammatory reaction generated is significant.1

To make your experience as comfortable as possible, SKINVIVE™ contains lidocaine, a mild local anaesthetic.1

Like all medical procedures, treatment with hyaluronic acid injections may cause side effects. For SKINVIVE™, these may include inflammatory reactions such as redness and swelling, bruising, lumps, thickening and hardening of skin and discolouration at the site of injection.1

These injection-site reactions are mainly mild or moderate and typically resolve within 1 week.4

Treatment with SKINVIVE™ may cause injection-site reactions.1 However, a licensed practitioner specialised in facial aesthetics will be trained to reduce the risk of side effects, like bruising or lumps.1

Treatment typically takes between 8 and 15 minutes,15,*** although it can vary depending on the areas treated. Your appointment time will be slightly longer to allow for a full consultation with your practitioner.

For 12 hours after SKINVIVE™ treatment, you should avoid using make-up.1

For 2 weeks after SKINVIVE™ treatment, you should avoid any extended exposure to the sun, UV rays or temperatures below 0°C.1 You should also avoid any sauna or steam room sessions during this time.1

See the SKINVIVE™ difference
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Explore high-definition Before & After photos of real patients and see transformative skin hydration results with SKINVIVE™.

EXPLORE BEFORE & AFTERS

Individual results may vary.

Find your nearest clinic

For a deep,‡ long-lasting§ injectable skin hydration treatment that helps you meet your unique beauty goals,1,4 speak to a practitioner about SKINVIVE™.

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SKINVIVE™ by JUVÉDERM® is an injectable implant used for the treatment, by filling, of superficial cutaneous depressions such as fine lines and for additional improvement of skin quality attributes such as hydration and elasticity.1

Footnotes

  • *Lasting up to 9 months as reported by 70.6% of patients. As reported by 127 of 131 patients (1 subject did not respond) in a composite satisfaction score, which includes how hydrated their facial skin looked.2
  • †Lasting up to 9 months as reported by 51.2% of patients. As reported by 127 of 131 patients (2 subjects did not respond) in a composite satisfaction score, which includes how refreshed their facial skin looked.2
  • ‡Skin hydration was measured using the MoistureMeterD instrument with the XS 5 and S 15 probes (depth of effective measurement: 0.5 and 1.5 mm, respectively).4
  • §Long-lasting is up to 9 months following a single treatment.4
  • ‖Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and
top-up treatment administered at Day 30 (n=31).4
  • The Fitzpatrick classification denotes six different skin types, skin colour and reaction to sun exposure (type I: burns easily, never tans; type II: burns easily, tans minimally with difficulty; type III: burns moderately, tans moderately and uniformly; type IV: burns minimally, tans moderately and easily; type V: rarely burns, tans profusely; type VI: never burns, tans profusely).6 In a randomised, evaluator-blind, delayed treatment control study involving 209 patients, the majority of patients had Fitzpatrick skin types III/IV (58.8%), followed by I/II (32.0%) and V/VI (9.2%).5 In a prospective, single-arm study of 131 patients, the majority of patients had Fitzpatrick skin type III (53.4%), followed by II (35.1%), IV (10.7%) and V (0.8%).4
  • **Lasting up to 9 months as reported by 64.6% of patients. As reported by 127 of 131 patients in a composite satisfaction score, which includes how clear their facial skin looked.2
  • ††Lasting up to 9 months as reported by 55.1% of patients. As reported by 127 of 131 patients in a composite satisfaction score, which includes how smooth their facial skin looked.2
  • ‡‡Lasting up to 9 months as reported by 63% of patients. As reported by 127 of 131 patients in a composite satisfaction score, which includes how radiant their facial skin looked.2
  • §§Lasting up to 9 months as reported by 67.7% of patients. As reported by 127 of 131 patients (3 subjects did not respond) in a composite satisfaction score, which includes satisfaction with their skin’s tone (colour).2
  • ‖‖Lasting up to 9 months as reported by 76.2% of patients. As reported by 127 of 131 patients (1 subject did not respond) in a composite satisfaction score, which includes how healthy their skin looked.2
  • ¶¶Data derived from a prospective, non-randomised, interventional, open-label study where 11 healthy patients (men [n=2] and women [n=9]) received intradermal VYC-12L treatment on the volar forearm. Clinical probes assessed skin quality at baseline and Months 1 and 3 post-treatment. Punch biopsies were collected at Months 1 and 3 post-treatment to evaluate histologic and genomic changes.12
  • ***Based on a survey done with 6 healthcare professional experts in skin quality treatments regarding their clinical experience with injection time in the area of the face.15

References

  1. Juvéderm® VOLITE DFU. 73655JR10. Revision 2019-09-09. 
  2. Ogilvie P et al. J Cosmet Dermatol. 2020;19(5):1065–1070.
  3. Purnamawati S et al. Clin Med Res. 2017;15(3-4);75–87.
  4. Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798.
  5. Alexiades M et al. Dermatol Surg. 2023;49(7):682–688.
  6. Sachdeva S. Indian J Dermatol Venereol Leprol. 2009;75(1):93–96.
  7. Belmontesi M et al. J Drugs Dermatol. 2018; 17(1):
83–88.
  8. Akinbiyi T et al. Plast Reconstr Surg Glob Open. 2020;8(10):e2763.
  9. Lipko-Godlewska S et al. Clin Cosmet Investig Dermatol. 2021;14:169–178.
  10. Khmaladze I et al. Clin Cosmet Investig Dermatol. 2020;13:1021–1040.
  11. Humphrey S et al. Dermatol Surg. 2021;47(7):974–981.
  12. Safa M et al. Clin Cosmet Investig Dermatol. 2022;15:411–426.
  13. Draelos Z. J Clin Aesthet Dermatol. 2012;5(7):53–56.
  14. Zarbafian M et al. Dermatol Surg. 2022;48(3):369–372.
  15. Allergan Aesthetics. Unpublished data. SKINVIVE™ time of injection. REF-116636. October 2023.

[Local markets to update reference 1 to locally available SKINVIVE™ DFU]

Models treated with SKINVIVE™. Individual results may vary.

Website produced and funded by Allergan Aesthetics, an AbbVie company.

Directions for consumers

This content is intended for [insert country name] adult (>18yrs) audience only. You should always consult a healthcare professional to help you decide if SKINVIVE™ by JUVÉDERM® is right for you and provide you with a full list of side effects.

Directions for healthcare professionals

Patients may experience potential side effects with SKINVIVE™ by JUVÉDERM® facial filler, which include inflammatory reactions (redness, oedema, erythema, etc.), haematomas, induration or nodules, staining or discolourations at injection site, etc. Please refer to SKINVIVE™ by JUVÉDERM® Directions for Use (DFU) for a full list of adverse events.1

Adverse events should also be reported. Reporting forms and information can be found at [insert local reporting information details]. Adverse events should be reported to Allergan Aesthetics [insert local contact details for AE reporting].

ALL-SKV-230019 | January 2024